Search results for " involvement"

Systems Approach to Eastern Baltic Coastal Zone Management

2020

Relying on the results of multivariate analysis of the re-analysis case studies from the BaltCoast project, specific features of integrated coastal management (ICM) approaches in Estonia, Latvia, Lithuania, and the Kaliningrad Oblast of the Russian Federation are highlighted in this paper. Eleven Eastern Baltic ICM case studies have been re-analyzed in-depth, which was the main focus of the present paper, covering a wide range of coastal landscapes, themes, policy issues, and ICM approaches. Five principal components explaining 84.86% of the total variance of ICM factor scores have been elicited by calculating rotation sums of squared loadings: (1) Stakeholder Involvement

Using the Intervention Mapping protocol to develop a family-based intervention for improving lifestyle habits among overweight and obese children: st…

2016

Abstract Background In light of the high prevalence of childhood overweight and obesity, there is a need of developing effective prevention programs to address the rising prevalence and the concomitant health consequences. The main aim of the present study is to systematically develop and implement a tailored family-based intervention for improving lifestyle habits among overweight and obese children, aged 6–10 years old, enhancing parental self-efficacy, family engagement and parent-child interaction. A subsidiary aim of the intervention study is to reduce the prevalence of overweight and obesity among those participating in the intervention study. Methods/design The Intervention Mapping p…

Central nervous system involvement in ALK-rearranged NSCLC : promising strategies to overcome crizotinib resistance

2016

ABSTRACT: Introduction: ALK rearranged Non Small Cell Lung Cancers (NSCLCs) represent a distinct subgroup of patients with peculiar clinic-pathological features. These patients exhibit dramatic responses when treated with the ALK tyrosine kinase inhibitor Crizotinib, albeit Central Nervous System (CNS) activity is much less impressive than that observed against extracranial lesions. CNS involvement has become increasingly observed in these patients, given their prolonged survival. Several novel generation ALK inhibitors have been developing to increase CNS penetration and to provide more complete ALK inhibition. Areas covered: The CNS activity of Crizotinib and novel generation ALK inhibito…

Congenital muscular dystrophy: from muscle to brain.

2016

Congenital muscular dystrophies (CMDs) are a wide group of muscular disorders that manifest with very early onset of muscular weakness, sometime associated to severe brain involvement. The histologic pattern of muscle anomalies is typical of dystrophic lesions but quite variable depending on the different stages and on the severity of the disorder. Recent classification of CMDs have been reported most of which based on the combination of clinical, biochemical, molecular and genetic findings, but genotype/phenotype correlation are in constant progression due to more diffuse utilization of the molecular analysis. In this article, the Authors report on CMDs belonging to the group of dystroglyc…

¿Atenuación del compromiso del hablante?: el caso de los evidenciales "por lo visto" y "se ve que"

2018

espanolBuena parte de la bibliografia sobre marcadores evidenciales en espanol senala la atenuacion del compromiso (o responsabilidad) de lo dicho como uno de sus rasgos definitorios. Sin embargo, tanto la nocion de atenuacion como la de compromiso del hablante se han empleado con distintas acepciones, segun los trabajos. En primer lugar, se revisan estas acepciones y se propone, siguiendo a Cornillie/Delbecque, distinguir las nociones compromiso del hablante de implicacion del hablante, las cuales funcionan de manera inversa en algunos usos evidenciales: (i) de las evidencias reportativas a las inferenciales conjeturales hay una escala de menos a mas implicacion del hablante; (ii) en las e…

Living with disability in a COVID-19 world

2021

Respiratory involvement in antineutrophil cytoplasmic antibody-associated vasculitides: a retrospective study based on POLVAS registry

2021

OBJECTIVES: The study aimed to characterise the Polish population of (ANCA)-associated vasculitides (AAV) with respiratory involvement (RI), in comparison to the subgroup without lung manifestations and the other cohorts. METHODS: Retrospective analysis of the Polish population of AAV with RI was conducted, based on data from the POLVAS registry. Standard descriptive statistics, χ2 test, and Mann-Whitney U test were used to perform comparisons. RESULTS: Among 461 cases qualified to this study, there were 316 cases with RI (68.5%), 206 with granulomatosis with polyangiitis (GPA) (65.2%), 80 with eosinophilic granulomatosis with polyangiitis (EGPA) (25.3%) and 30 with microscopic polyangiitis…

Tinkering with the two-to-one interview: Reflections on the use of two interviewers in qualitative constructionist inquiry

2021

Abstract Typically, qualitative interviews implicate a single interviewer. In this article, we consider an alternative comprising the simultaneous, active involvement of two interviewers. We base our considerations on experiences using the two-to-one interview in a nationwide research project on disability and physical activity. In addition to untapping and developing a qualitative interview method, the article provides an example in action of tinkering in qualitative inquiry. Tinkering entails a constant questioning of what to do, what is best, and what is appropriate within each moment of the research. Echoing social constructionist scholars, we argue that this flexible approach is useful…

Older people’s participation in political organizations: The role of generativity and its impact on well-being

2017

Aging population has increased a global concern to keep seniors active and healthy. Civic participation, in particular, has been highlighted for its social and community benefits and its impact on elders’ health and well-being. To date, however, most studies have explored volunteering; other types of civic activities, such as political participation, are largely overlooked. This study analyzes the relationship between older people’s active involvement in political organizations, generativity, and hedonic and eudaimonic well-being. We selected two samples of Spanish older people: a sample of elders actively involved in political organizations (n = 97) and a comparison group (n = 85). Measure…

Immunophenotypic profile and role of adhesion molecules in splenic marginal zone lymphoma with bone marrow involvement

2005

Abstract Splenic Marginal Zone Lymphoma (SMZL), with or without villous lymphocytes (VL+/-), is a low-grade lymphoproliferative disorder with constant involvement of the bone marrow (BM). Different BM infiltration patterns, mainly intra-sinusoidal, interstitial and nodular, have been described. Adhesion molecules (AMs) constitute a heterogeneous group of antigenic receptors playing a major role in leukocyte recruitment, in lymphocyte homing and in cellular-mediated immune response. Evolution and pattern of the BM infiltrate could be influenced by a variable expression of AM on SMZL lymphocytes. The degree and pattern of BM infiltration and the immunohistochemical expression of AM (H-CAM, BL…